Journal Articles


  • Toscano-Márquez, B., Cook, A.A., Rice, M., Smileski, A., Vieira-Lomasaney, K., Charron, F., McKinney, R.A., and A.J. Watt (2021) Molecular identity and location influence Purkinje cell vulnerability in ARSACS mice. Frontiers in Cellular Neuroscience
    • Press release for this article can be found here.
    • This work has been featured on CBC Radio Let’s Go here.
  • Lang-Ouellette, D., Gruver, K.M., Smith-Dijak, A., Blot, F.G.C., Stewart, C., de Vanssay de Blavous, P., Li, C., van Eitrem, C., Rosen, C., Faust, P.L., Schonewille, M., and A.J. Watt (2021) Purkinje cell axonal swellings enhance axonal spike fidelity and cerebellar function. Nature Communications 12 (4129)
    • Press release for this article can be found here.
  • Hooshmandi, M. Truong, V.T., Fields, E., Thomas, R.E., Wong, C., Sharma, V., Gantois, I., Roque, P.S. Chalkiadaki, K., Wu, N., Chakraborty, A., Tahmasebi, S., Prager-Khoutorsky, M., Sonenberg, N., Suvrathan, A., Watt, A.J., Gkogkas, C.G., and Khoutorsky, A (2021). 4E-BP2-dependent translation in cerebellar Purkinje cells controls spatial memory but not autism-like behaviors. Cell



  • Gruver, K. M., and A.J. Watt (2019). Optimizing Optogenetic Activation of Purkinje Cell Axons to Investigate the Purkinje cell – DCN synapse. Frontiers in Synaptic Neuroscience. 11 (31)
  • Leung, S., McKinney, R.A. and A.J. Watt (2019) Brain development: the impact of light during the night. eLife 2019;8:e52364 doi: 10.7554/eLife.52364
  • Li, L., Jayabal, S., Ghorbani, M., Legault, L.-M., McGraw, S., Watt, A.J., and X.-J. Yang. (2019). ATAT1 regulates forebrain development and stress-induced tubulin hyperacetylation. Cellular and Molecular Life Sciences
  • Larivière, R., Sgarioto, N., Toscano-Márquez, B., Gaudet, R., Choquet, K., McKinney, R.A., Watt, A.J., and B. Brais (2019). Sacs R272C missense homozygous mice develop an ataxia phenotype. Molecular Brain 12: 19.


  • Ady, V., Toscano-Márquez, B., Nath, M.,Chang, P. K.Y., Hui, J., Cook, A., Charron, F., Larivière, R., Brais, B., McKinney, R.A., and A.J. Watt (2018) Altered synaptic and firing properties of cerebellar Purkinje cells in a mouse model of ARSACS.Journal of Physiology. 596(17): 4253-4267.


  • Jayabal, S., Ljungberg, L., and A.J. Watt (2017) Transient cerebellar alterations during development prior to disease onset in a mouse model of spinocerebellar ataxia type 6. Journal of Physiology 595(3): 949-966.


  • Ljungberg, L., Lang-Ouellette, D., Yang, A., Quilez, S., Jayabal, S., and A.J. Watt (2016). Transient developmental Purkinje cell axonal torpedoes in healthy and ataxic mouse cerebellum. Frontiers in Cellular Neuroscience 10: 248.
  • Jayabal, S., Chang, H.H.V., Cullen, K.E., and A.J. Watt (2016) 4-Aminopyridine reverses ataxia and cerebellar firing deficiency in a mouse model of spinocerebellar ataxia type 6. Scientific Reports 6: 29489
  • Abrahamsson, T., Lalanne, T, Watt, A.J., and P.J. Sjöström (2016) Long-term potentiation by theta-burst stimulation using extracellular field potential recordings in acute hippocampal slices. Cold Spring Harbor Protocols doi:10.1101/pdb.prot091298
  • Abrahamsson, T., Lalanne, T, Watt, A.J., and P.J. Sjöström (2016) In vitro investigation of synaptic plasticity. Cold Spring Harbor Protocols doi:10.1101/pdb.top087262


  • Jayabal, S., Ljungberg, L., Erwes, T., Cormier, A., Quilez, S., El Jaouhari, S., and A.J. Watt (2015) Rapid onset of motor deficits in a mouse model of spinocerebellar ataxia type 6 precedes late cerebellar degeneration. eNeuro 2(6): e00094-15.2015 1-18


  • Ferreira, T.A., Blackman, A.V., Oyrer, J., Chung, A.J., Jayabal, S.*, Watt, A.J., Sjostrom, P.J., and D.J. van Meyel. (2014) Neuronal morphometry directly from bitmap images. Nature Methods, 11: 982-984


  • Costa, R. P., Watt, A.J., and P.J. Sjöström. (2013) How to train a neuron. eLife 10.7554/eLife.00491



  • Watt, A.J., and N.S. Desai. (2010) Homeostatic plasticity and STDP: keeping a neuron’s cool in a fluctuating world. Frontiers in Synaptic Neuroscience 2:5


  • Watt, A.J., Cuntz, H., Mori, M., Nusser, Z., Sjöström, P.J and Häusser, M. (2009). Traveling waves in developing cerebellar cortex mediated by asymmetrically connected Purkinje cells. Nature Neuroscience, 12: 463-473


  • Watt, A.J., Sjöström, P.J., Häusser, M., Nelson, S.B., and Turrigiano, G.G. (2004). A proportional but slower NMDA potentiation follows AMPA potentiation in LTP. Nature Neuroscience, 7: 518-524


  • Pratt, K.G., Watt, A.J., Griffith, L.C., Nelson, S.B., and Turrigiano, G.G. (2003). Activity-dependent remodeling of presynaptic inputs by postsynaptic expression of activated CaMKII. Neuron, 39: 269-281 DOI:



  • Billon, N., Carlisi, D., Datto, M.B., van Grunsven, L.A., Watt, A.J., Wang, X.-F., and Rudkin, B.B. (1999). Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation. Oncogene18: 2872-2882

Book Chapters

  • Gruver, K. M., and A.J. Watt (2020). “Optimizing Optogenetic Activation of Purkinje Cell Axons to Investigate the Purkinje cell – DCN synapse” in Methods for Synaptic Interrogation. Frontiers Media SA. Edited by Feldmeyer, D., Wesseling, J.F., and P.J. Sjöström. p. 201-208.  
  • Jayabal, S., and A.J. Watt (2019).“Turning on the juice: the development of physiological activity in the cerebellum” in  Handbook of the Cerebellum and Cerebellar Disorders, 2nd edition. Springer Publishing.Edited by Manto, M., Gruol, D.L., Schmahmann, J.D., Koibushi, N., and Sillitoe, R.V.
  • Abrahamsson, T., Lalanne, T, Watt, A.J., and P.J. Sjöström. (2017). “In Vitro investigation of Synaptic Plasticity” in Ion Channels. Cold Spring Harbor Press. Edited by Kammermeier, P., Duguid, I., and S. Brenowitz. 
  • Watt, A.J., and N.S. Desai. “Homeostatic plasticity and STDP: keeping a neuron’s cool in a fluctuating world” in Spike-Timing-Dependent Plasticity: A Comprehensive Overview. Frontiers Media SA, 2012, p. 240 -255